| Product Name | CRHSP-24 Antibody (H-36) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CRHSP-24 (calcium-regulated heat-stable protein 24) is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). A ubiquitously expressed protein, CRHSP-24 interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is thought to play a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues. CRHSP-24 is phosphorylated on Ser 52 by Akt-1 (PKBå) in response to IGF-1, on Ser 52 by Akt-1 and RSK in response to EGF, and on Ser 41 in the absence of IGF-1/EGF by a DYRK isoform or another proline-directed protein kinase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CRHSP-24 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 10-45 mapping near the N-terminus of CRHSP-24 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 10-45 mapping near the N-terminus of CRHSP-24 of human origin |
| Entrez Gene | 23589 |
|---|
| Application Notes | recommended for detection of CRHSP-24 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
