Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p14-p13 and 10q26.1, respectively.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISAGSChIP
recommended for detection of Emx1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-50 mapping at the N-terminus of Emx1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-50 mapping at the N-terminus of Emx1 of human origin
Western blot analysis of Emx1 expression in mouse liver tissue extract.
Application
Western blot analysis of Emx1 expression in non-transfected: (A) and mouse Emx1 transfected: (B) 293 whole cell lysates.
Application Notes
recommended for detection of Emx1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.