Application
Western blot analysis of Selenoprotein P expression in Hep G2 whole cell lysate.Application
Western blot analysis of Selenoprotein P expression in K-562 whole cell lysate.Application
Western blot analysis of Selenoprotein P expression in non-transfected 293T: (A), mouse Selenoprotein P transfected 293T: (B) and human PBL (C) whole cell lysates.| Product Name | Selenoprotein P Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Selenium is an essential trace element that is incorporated as selenocysteine into the primary structure of selenoproteins. Nutritional deficiency of selenium decreases selenoprotein concentrations and leads to pathologic conditions. Most of the known selenoproteins are members of the glutathione peroxidase or iodothyronine deiodinase families. Selenoprotein P (SEPP1) is a major selenoprotein that is not a member of those families. It is an extracellular glycoprotein that is present in several isoforms and is the only selenoprotein known to contain multiple selenocysteine residues. Selenoprotein P is a heparin-binding protein that appears to be associated with endothelial cells and has been implicated as an oxidant defense in the extracellular space. Although there is evidence of several isoforms of the protein, all of them share the same amino-terminal sequence and therefore are likely products of the same gene. The gene which encodes Selenoprotein P maps to human chromosome 5q31. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Selenoprotein P of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 82-381 mapping at the C-terminus of Selenoprotein P of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 82-381 mapping at the C-terminus of Selenoprotein P of human origin |
| Entrez Gene | 6414 |
|---|
Application
Western blot analysis of Selenoprotein P expression in Hep G2 whole cell lysate.
Application
Western blot analysis of Selenoprotein P expression in K-562 whole cell lysate.
Application
Western blot analysis of Selenoprotein P expression in non-transfected 293T: (A), mouse Selenoprotein P transfected 293T: (B) and human PBL (C) whole cell lysates.| Application Notes | recommended for detection of Selenoprotein P of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
