Application
Western blot analysis of T2R10 expression in SCC-4 (A) and SCC-25 (B) whole cell lysates and human skeletal muscle tissue extract (C).| Product Name | T2R10 Antibody (D-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | T2R10 (taste receptor type 2 member 10), also known as TRB2 (taste receptor family B member 2) or TAS2R10, is a 307 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Members of the T2R family are genetically linked to loci that influence bitter perception in mice and humans. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R10 is found exclusively in gustducin-positive cells. T2R10 signals through PLC ∫2 and the calcium-regulated cation channel TRPM5. The gene that encodes T2R10 maps to human chromosome 12p13. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of T2R10 of human origin by WB, IP, IF and ELISA non cross-reactive with other T2R family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of T2R10 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of T2R10 of human origin |
| Entrez Gene | 50839 |
|---|
Application
Western blot analysis of T2R10 expression in SCC-4 (A) and SCC-25 (B) whole cell lysates and human skeletal muscle tissue extract (C).| Application Notes | recommended for detection of T2R10 of human origin by WB, IP, IF and ELISA non cross-reactive with other T2R family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
