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TF Antibody (FL-295)

Catalog Number:OM211526
OM211526
Discount Price
OM211526-100ul
1~2 Week
100ul
OM211526-50ul
50ul
OM211526-20ul
20ul
1~2 Week
Product Profile
Product Name TF Antibody (FL-295)
Antibody Type Primary Antibodies
Modification Notes Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a Prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III) is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIPIFIHCELISA
recommended for detection of TF of human and, to a lesser extent, mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Alternative Names epitope corresponding to amino acids 15-295 mapping at the C-terminus of TF of human origin
Tissue Specificity epitope corresponding to amino acids 15-295 mapping at the C-terminus of TF of human origin
Database Links
Entrez Gene 2152
Application

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix tissue showing membrane and cytoplasmic staining of squamous epithelial cells.

Application

Western blot analysis of TF expression in non-transfected 293T: (A), mouse TF transfected 293T: (B) and JEG-3 (C) whole cell lysates.

Application

Western blot analysis of TF expression in non-transfected 293T: (A), mouse TF transfected 293T: (B) and JEG-3 (C) whole cell lysates.

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharinx tissue showing membrane and cytoplasmic staining of surface epithelial cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Application

Western blot analysis of TF expression in mouse placenta tissue extract.
Application Notes recommended for detection of TF of human and, to a lesser extent, mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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