Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The FAM26F gene product has been provisionally designated FAM26F pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FAM26F of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA non cross-reactive with FAM26D or FAM26E also reactive with additional species, including canine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of FAM26F of human origin
Tissue Specificity
epitope mapping near the C-terminus of FAM26F of human origin
Western blot analysis of FAM26F expression in non-transfected: (A) and mouse FAM26F transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of FAM26F of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA non cross-reactive with FAM26D or FAM26E also reactive with additional species, including canine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.