| Product Name | TORC3 Antibody (S-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TORC3 (transducer of regulated cAMP response element-binding protein 3), also known as CRTC3 (CREB-regulated transcription coactivator 3), is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TORC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with TORC1 or TORC2 also reactive with additional species, including porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TORC3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TORC3 of human origin |
| Entrez Gene | 64784 |
|---|
| Application Notes | recommended for detection of TORC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with TORC1 or TORC2 also reactive with additional species, including porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
