| Modification Notes |
SLC7A10 (solute carrier family 7, (neutral amino acid transporter, y+ system) member 10), also known as ASC1 (asc-type amino acid transporter 1), is a 523 amino acid multi-pass membrane protein that belongs to the amino acid-polyamine-organocation (APC) superfamily. SLC7A10 forms a disulfide-linked heterodimer with CD98 to regulate high-affinity transport of several neutral amino acids, including D-serine. Expressed in pancreas, skeletal muscle, placenta, heart, brain, kidney, lung and liver, SLC7A10 is encoded by a gene that maps to human chromosome 19q13.11 and is considered a candidate gene for cystinuria. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. |