| Product Name | ACOT7 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT7 (acyl-CoA thioesterase 7), also known as BACH (brain acyl-CoA hydrolase), LACH or CTE-II, is a 380 amino acid protein that is expressed as 6 alternatively spliced isoforms which localize to either the cytoplasm or the mitochondria. Functioning as a homodimer that contains 2 acyl coenzyme A hydrolase domains, ACOT7 plays an important role in regulating acyl-CoA levels within the body and is thought to specifically participate in proper brain physiology and function. Decreased ACOT7 expression may be associated with mesial temporal lobe epilepsy, a form of focal epilepsy that is characterized by simple or complex seizures. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ACOT7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 81-380 mapping at the C-terminus of ACOT7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 81-380 mapping at the C-terminus of ACOT7 of human origin |
| Entrez Gene | 11332 |
|---|
| Application Notes | recommended for detection of ACOT7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
