Application
Western blot analysis of SGSM3 expression in MIA PaCa-2 whole cell lysate.| Product Name | SGSM3 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Small G proteins act as molecular switches for regulation of a variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. SGSM3 (small G protein signaling modulator 3), also known as MAP (merlin-associated protein), RUSC3 or RUTBC3, is a 749 amino acid widely expressed cytoplasmic protein that belongs to the small G protein signaling modulator family. Existing as two alternatively spliced isoforms, SGSM3 contains a Rab-GAP TBC domain, a RUN domain and a SH3 domain. The degradation of SGSM3 is promoted by its interaction with connexin 43. SGSM3 is associated with several members of the Ras-related superfamily of guanine nucleotide binding proteins and is suggested to play a cooperative role in NF2-mediated growth suppression of cells. SGSM3 is encoded by a gene located on human chromosome 22q13.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SGSM3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SGSM3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SGSM3 of human origin |
| Entrez Gene | 27352 |
|---|
Application
Western blot analysis of SGSM3 expression in MIA PaCa-2 whole cell lysate.| Application Notes | recommended for detection of SGSM3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
