| Product Name | FCHSD1 Antibody (D-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | FCHSD1 (FCH and double SH3 domains protein 1) is a 690 amino acid protein that contains one FCH domain and two SH3 domains. FCHSD1 exists as three isoforms as a result of alternative splicing events. The gene encoding FCHSD1 maps to chromosome 5, which is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of FCHSD1 isoforms 1-3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with FCHSD2 also reactive with additional species, including equine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of FCHSD1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of FCHSD1 of human origin |
| Entrez Gene | 89848 |
|---|
| Application Notes | recommended for detection of FCHSD1 isoforms 1-3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with FCHSD2 also reactive with additional species, including equine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
