| Product Name | PAMR1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | PAMR1 (peptidase domain containing associated with muscle regeneration 1), also known as RAMP or FP938, is a 720 amino acid secreted protein that belongs to the peptidase S1 family. Consisting of one CUB domain, an EGF-like domain, a peptidase S1 domain and two sushi (CCP/SCR) domains, PAMR1 may participate in regeneration of skeletal muscle. PAMR1 is strongly down-regulated in muscle cell lines derived from Duchenne muscular dystrophy (DMD) patients compared to a normal muscle cell line. DMD is the second most common genetically inherited disease in humans and is characterized by progressive limb-girdle distribution of muscle weakness. PAMR1 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 11, which contains 135 million base pairs and 1,400 genes, making up around 4% of human genomic DNA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PAMR1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 421-720 mapping at the C-terminus of PAMR1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 421-720 mapping at the C-terminus of PAMR1 of human origin |
| Entrez Gene | 25891 |
|---|
| Application Notes | recommended for detection of PAMR1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
