| Product Name | Apollon Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Inhibitor of apoptosis proteins (IAP) are a family of proteins that have baculovirus IAP repeat (BIR) domains and inhibits apoptosis. Apollon (also known as BRUCE or baculoviral IAP repeat-containing protein 6 (BIRC6)) is a large protein that binds to, ubiquitinates and facilitates proteasomal degradation of second mitochondria-derived activator of caspase (Smac) and caspase-9. Apollon can be associated with the membrane of the Golgi system and is expressed in brain cancer cells. Apollon may play a role in tumorigenesis and drug resistance of some brain cancer cell lines. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Apollon of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-420 mapping near the N-terminus of Apollon of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-420 mapping near the N-terminus of Apollon of human origin |
| Entrez Gene | 57448 |
|---|
| Application Notes | recommended for detection of Apollon of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
