| Product Name | MoCo Sulfurase Antibody (T-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The biosynthesis of molybdenum cofactor is a highly conserved pathway that leads to the activation of molybdenum, a transitional element used as a metal hetero-atom in the active site of certain enzymes. MoCo Sulfurase (Molybdenum cofactor sulfurase), also known as HMCS and MOS, is a 888 amino acid enzyme that sulfurates molybdenum cofactor so that it can be utilized by xanthine dehydrogenase and aldehyde oxidase. Defects in the gene encoding MoCo Sulfurase is the cause of type II xanthinuria, a condition that is characterized by excretion of large amounts of xanthine in urine and the subsequent formation of xanthine stones. Due to the deficiencies of xanthine dehydrogenase and aldehyde oxidase, patients suffering from type II xanthinuria also cannot metabollize allopurinol into oxypurinol, leading to decreases in uric acid formation and purine synthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of MoCo Sulfurase of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MoCo Sulfurase of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MoCo Sulfurase of human origin |
| Entrez Gene | 55034 |
|---|
| Application Notes | recommended for detection of MoCo Sulfurase of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
