Western blot analysis of C2orf24 expression in HeLa (A), Jurkat (B), HEK293 (C), NIH/3T3 (D) and SW480 (E) whole cell lysates and mouse brain tissue extract (F).
The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The C2orf24 gene product has been provisionally designated C2orf24 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of C2orf24 of human origin and 1810031K17Rik of mouse origin of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other C2orf family members
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the N-terminus of C2orf24 of human origin
Tissue Specificity
epitope mapping near the N-terminus of C2orf24 of human origin
Western blot analysis of C2orf24 expression in HeLa (A), Jurkat (B), HEK293 (C), NIH/3T3 (D) and SW480 (E) whole cell lysates and mouse brain tissue extract (F).
Application Notes
recommended for detection of C2orf24 of human origin and 1810031K17Rik of mouse origin of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other C2orf family members
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.