Application
Western blot analysis of LMX1A expression in rat skeletal muscle tissue extract.| Product Name | LMX1A Antibody (H-52) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | LMX1A, also called LMX-1.1 or LIM homeobox transcription factor 1 å, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. Two isoforms of LMX1A exist due to alternative splicing. Isoform 1 represents the full length protein and is expressed in many tissues including fetal brain, but is absent in heart, liver, spleen and testis. The second isoform, designated LMX1A-4AB, lacks amino acids 1-249 and is expressed in testis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LMX1A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 260-311 mapping near the C-terminus of LMX1A of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 260-311 mapping near the C-terminus of LMX1A of human origin |
| Entrez Gene | 4009 |
|---|
Application
Western blot analysis of LMX1A expression in rat skeletal muscle tissue extract.| Application Notes | recommended for detection of LMX1A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
