Application
Western blot analysis of ING1 expression in mouse brain tissue extract.| Product Name | ING1 Antibody (H-220) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ING1 (Inhibitor of growth protein 1) is a 422 amino acid protein encoded by the human gene ING1. ING1 belongs to the ING family and contains one PHD-type zinc finger. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene, ING1 is a nuclear protein with several known isoforms, three of which are designated p47ING1 (ING1 precursor), p33ING1 and p24ING1, whose expression varies per tissue. The p33ING1 isoform is expressed in all normal tissues and cells, while the p24ING1 isoform is expressed in testis, liver, and kidney, and is weakly expressed in colon and brain, but not in breast or cultured melanocytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ING1 of mouse, rat and human origin by WB, IP, IF and ELISA may cross-react with ING2 also reactive with additional species, including canine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 331-442 mapping at the C-terminus of ING1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 331-442 mapping at the C-terminus of ING1 of human origin |
| Entrez Gene | 3621 |
|---|
Application
Western blot analysis of ING1 expression in mouse brain tissue extract.| Application Notes | recommended for detection of ING1 of mouse, rat and human origin by WB, IP, IF and ELISA may cross-react with ING2 also reactive with additional species, including canine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
