| Product Name | Neuritin Antibody (FL-142) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF). NGF is a soluble peptide that promotes the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4, also designated NT-5). Neuritin is a glycosylphosphatidylinositol-anchored protein that is induced by neural activity as well as by BDNF and NT-3. Neuritin modulates neurite growth extracellularly and is present in development and in the adult nervous system, indicating its involvement in neuronal plasticity. In addition to BDNF induction of Neuritin, it has been shown that both Neuritin and BDNF are induced by light stimulation of the visual cortex. Neuritin appears to be located downstream of BDNF and may mediate some of the effects of BDNF |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Neuritin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-142 representing full length Neuritin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-142 representing full length Neuritin of human origin |
| Entrez Gene | 51299 |
|---|
| Application Notes | recommended for detection of Neuritin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
