UNC93A (unc-93 homolog A), also known as HmUNC-93A, is a 457 amino acid multi-pass membrane protein and human homolog of C. elegans unc-93, a protein involved in the coordination and regulation of muscle contraction. Expressed in testis, small intestine, spleen, prostate and ovary, UNC93A is encoded by a gene located on human chromosome 6. Human chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of UNC93A of human origin by WB, IP, IF, IHC(P) and ELISA non cross-reactive with UNC93B1 or UNC93B6
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of UNC93A of human origin
Tissue Specificity
epitope mapping near the C-terminus of UNC93A of human origin