| Product Name | pescadillo Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The deduced 588 amino acid pescadillo protein (also designated PES1) is the human homolog of zebrafish pescadillo and shows 74% sequence identity to the zebrafish sequence. During the first three days of zebrafish development, pescadillo is highly expressed, but no expression is observed in any adult tissue except the ovary. The mouse pescadillo sequence contains a BRCT (breast cancer C-terminal) domain, originally identified in BRCA1, a p53-binding protein. In mouse tissue, pescadillo is ubiquitiously expressed with highest levels of expression in adult and fetal liver, followed by adult kidney and testis; the lowest expression is found in skeletal muscle. Pescadillo upregulation occurs in human breast carcinoma cells and in primary glioblastoma cells. Proliferation only occurs in HeLa cells that express pescadillo. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of pescadillo isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of pescadillo of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of pescadillo of human origin |
| Entrez Gene | 23481 |
|---|
| Application Notes | recommended for detection of pescadillo isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
