Application
Western blot analysis of OATP-H expression in KNRK (A) and NRK (B) whole cell lysates and mouse kidney tissue extract (C).| Product Name | OATP-H Antibody (E-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-H (organic anion transporter F), also known as SLCO4C1 (solute carrier organic anion transporter family member 4C1), OATPX or SLC21A14 (solute carrier family 21 member 20), is a 724 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-H mediates the Na+-independent, high affinity transport of pharmacological substances such as thyroxine, digoxin, methotrexate, cAMP and ouabain. OATP-H is also thought to be involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin. OATP-H is expressed highly in kidney, with lower expression found in fetal kidney and liver. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of OATP-H of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Oatp family members also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of OATP-H of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of OATP-H of human origin |
| Entrez Gene | 353189 |
|---|
Application
Western blot analysis of OATP-H expression in KNRK (A) and NRK (B) whole cell lysates and mouse kidney tissue extract (C).| Application Notes | recommended for detection of OATP-H of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Oatp family members also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
