Application
Western blot analysis of SH3YL1 expression in TT whole cell lysate (A) and mouse kidney tissue extract (B).Application
Western blot analysis of SH3YL1 expression in rat small intestine tissue extract.Application
Western blot analysis of SH3YL1 expression in non-transfected: (A) and human SH3YL1 transfected: (B) 293T whole cell lysates.| Product Name | SH3YL1 Antibody (G-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | SH3YL1 (SH3 domain-containing YSC84-like protein 1), alternately known as RAY, is a 342 amino acid protein that plays a role in hair follicle formation. Expressed at high levels during meiosis, SH3YL1 is found in stomach, kidney, colon, small intestine and skin (where it localizes to the hair shaft, bulb and outer root sheath). SH3YL1 expression is highest during mid and late anagen phases of the hair-growth cycle and is found at lower levels during the catagen, telogen and early anagen phases. SH3YL1 contains one SH (Scr homology) 3 domain, belongs to the SH3YL1 family and interacts with SH3D19. Five SH3YL1 isoforms are produced as a result of alternative splicing events, and the gene encoding SH3YL1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, Sitosterolemia and Alström syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SH3YL1 isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with SH3YL1 isoform 5 also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SH3YL1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SH3YL1 of human origin |
| Entrez Gene | 26751 |
|---|
Application
Western blot analysis of SH3YL1 expression in TT whole cell lysate (A) and mouse kidney tissue extract (B).
Application
Western blot analysis of SH3YL1 expression in rat small intestine tissue extract.
Application
Western blot analysis of SH3YL1 expression in non-transfected: (A) and human SH3YL1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SH3YL1 isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with SH3YL1 isoform 5 also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
