Stomatin is an integral membrane protein found in lipid/protein-rich microdomains of almost all human tissues. It was named after the rare human disease haemolytic anaemia hereditary stomatocytosis. Stomatin is implicated in signal transduction and cell communication, and it may regulate cation movement through ion channels and transporters. Absence of Stomatin may cause Na+ and K+ ions to leak into and from erythrocytes. A second function of Stomatin may be to act as a cytoskeletal anchor. Stomatin is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein. It contains a single hydrophobic domain, close to the N-terminus, and a phosphorylation site.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Stomatin of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-45 mapping at the N-terminus of Stomatin of human origin
Tissue Specificity
epitope corresponding to amino acids 1-45 mapping at the N-terminus of Stomatin of human origin