Western blot analysis of SerpinB12 expression in K-562 (A), HeLa (B), JAR (C), Jurkat (D) and A549 (E) whole cell lysates and mouse lymph node tissue extract (F).
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SERPINB12 appears to be an inhibitor of trypsin-like serine proteinases, including mast cell tryptases.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SerpinB12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Serpin famiy members also reactive with additional species, including equine, canine and bovine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of SerpinB12 of human origin
Tissue Specificity
epitope mapping within an internal region of SerpinB12 of human origin
Western blot analysis of SerpinB12 expression in K-562 (A), HeLa (B), JAR (C), Jurkat (D) and A549 (E) whole cell lysates and mouse lymph node tissue extract (F).
Application Notes
recommended for detection of SerpinB12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Serpin famiy members also reactive with additional species, including equine, canine and bovine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.