| Modification Notes |
Cysteine-rich protein 2 (CRIP2) is a 208 amino acid protein that contains two LIM zinc-binding domains that link to short glycine-rich repeats, and a potential nuclear localization signal. CRIP proteins participate in the organization of multiprotein complexes, both in the cytoplasm, where they participate in cytoskeletal remodeling, and in the nucleus, where they facilitate smooth muscle differentiation. CRIP2 tissue expression is widespread, with highest levels in the heart. The human CRIP2 gene maps to chromosome 14q32.33. |