| Product Name | ALOXE3 Antibody (N-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ALOXE3 (arachidonate lipoxygenase 3), also known as E-LOX or eLOX3, is a 711 amino acid protein that is involved in lipid metabolism and contains one lipoxygenase domain and one PLAT domain. Expressed predominately in skin, ALOXE3 uses iron as a cofactor to introduce oxygen into polyunsaturated fatty acids and is thought to play an important role in the catabolism of leukotrienes (arachidonic acid-derived compounds which participate in inflammation and hypersensitivity). Defects in the gene encoding ALOXE3 are the cause of non-bullous congenital ichthyosiform erythroderma (NCIE), a skin disorder characterized by an abnormal cornification of the epidermis, with symptoms including scaling and red skin, as well as painful fissures resulting from palmoplantar keratoderma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ALOXE3 of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of ALOXE3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of ALOXE3 of human origin |
| Entrez Gene | 59344 |
|---|
| Application Notes | recommended for detection of ALOXE3 of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
