Application
Western blot analysis of TADA3L expression in non-transfected: (A) and mouse TADA3L transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TADA3L expression in HeLa (A), NIH/3T3 (B) and OV-90 (C) whole cell lysates.| Product Name | TADA3L Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L. ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex is the human homolog of the yeast SAGA complex. ADA3 interacts with the E6 gene and is a target of E6-induced degradation. ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants. ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TADA3L of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-286 mapping at the N-terminus of TADA3L of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-286 mapping at the N-terminus of TADA3L of human origin |
| Entrez Gene | 10474 |
|---|
Application
Western blot analysis of TADA3L expression in non-transfected: (A) and mouse TADA3L transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TADA3L expression in HeLa (A), NIH/3T3 (B) and OV-90 (C) whole cell lysates.| Application Notes | recommended for detection of TADA3L of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
