| Product Name | Mx2 Antibody (H-58) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Mx2 of human origin by WB,IHC, IP, IF and ELISAWB:1:100~1:200 IHC:1:10~1:50 IF:1:20~1:100 IP:1:20~1:100 ELISA:1:1000~5000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 602-650 mapping near the C-terminus of Mx2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 602-650 mapping near the C-terminus of Mx2 of human origin |
| Entrez Gene | 4600 |
|---|
| Application Notes | recommended for detection of Mx2 of human origin by WB,IHC, IP, IF and ELISAWB:1:100~1:200 IHC:1:10~1:50 IF:1:20~1:100 IP:1:20~1:100 ELISA:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
