Application
Western blot analysis of KIAA1704 expression in non-transfected 293T: (A), human KIAA1704 transfected 293T: (B) and HeLa (C) whole cell lysates.| Product Name | KIAA1704 Antibody (K-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | KIAA1704, also known as LSR7 (Lipopolysaccharide-specific response protein 7), is a 340 amino acid protein that is encoded by a gene which maps to chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. There are four isoforms of KIAA1704 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KIAA1704 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform 4 also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of KIAA1704 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of KIAA1704 of human origin |
| Entrez Gene | 55425 |
|---|
Application
Western blot analysis of KIAA1704 expression in non-transfected 293T: (A), human KIAA1704 transfected 293T: (B) and HeLa (C) whole cell lysates.| Application Notes | recommended for detection of KIAA1704 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform 4 also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
