Application
Western blot analysis of CLLD6 expression in PC-12 whole cell lysate.| Product Name | CLLD6 Antibody (N-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CLLD6 (chronic lymphocytic leukemia deletion region gene 6 protein), also known as SPRYD7 (SPRY domain-containing protein 7) or C13orf1, is a 196 amino acid protein that contains one B30.2/SPRY domain. Expression of CLLD6 is found at highest levels in heart, skeletal muscle and testis, with lower levels found in thymus, peripheral blood leukocytes, lymph node and bone marrow. Existing as two alternatively spliced isoforms, CLLD6 maps to human chromosome 13, which comprises nearly 4% of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CLLD6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of CLLD6 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of CLLD6 of human origin |
| Entrez Gene | 57213 |
|---|
Application
Western blot analysis of CLLD6 expression in PC-12 whole cell lysate.| Application Notes | recommended for detection of CLLD6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
