Application
Western blot analysis of L-type Ca++ CP γ6 expression in HeLa (A) and K-562 (B) whole cell lysates.Application
Western blot analysis of L-type Ca++ CP γ6 expression in non-transfected 293T: (A), human L-type Ca++ CP γ6 transfected 293T: (B), Y79 (C), ARPE-19 (D), SK-N-MC (E) and H4 (F) whole cell lysates.Application
Western blot analysis of L-type Ca++ CP γ6 expression in WI 38 whole cell lysate.Application
Western blot analysis of L-type Ca++ CP γ6 expression in Hep G2 whole cell lysate.| Product Name | L-type Ca++ CP γ6 Antibody (L-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Voltage-dependent calcium channels are important for the release of neurotransmitters in neurons. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an å1 subunit, a ∫ subunit, a © subunit, and an å2∂ subunit. The © subunit is encoded by eight genes, ©1-©8, and functions by influencing the properties of calcium current. L-type Ca++ CP ©6 (voltage-dependent calcium channel subunit ©6), also called CACNG6, belongs to the CACNG subfamily of the PMP-22/EMP/MP20 family. It is a membrane protein with four transmembrane domains, an N-linked glycosylation site in the first extracellular loop and cytoplasmic N- and C-termini. CACNG is expressed in a variety of tissues including fetal and adult brain. L-type Ca++ CP ©6 is most closely related to family member CACNG1. Both subunits lack the PSD-95/DLG/ZO-1(PDZ) binding motif. L-type Ca++ CP ©6 may function to stabilize the calcium channel in an inactivated state. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of L-type Ca++ CP &gamma 6 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of L-type Ca++ CP γ6 of human origin by WB, IP and ELISA |
| Entrez Gene | 59285 |
|---|
Application
Western blot analysis of L-type Ca++ CP γ6 expression in HeLa (A) and K-562 (B) whole cell lysates.
Application
Western blot analysis of L-type Ca++ CP γ6 expression in non-transfected 293T: (A), human L-type Ca++ CP γ6 transfected 293T: (B), Y79 (C), ARPE-19 (D), SK-N-MC (E) and H4 (F) whole cell lysates.
Application
Western blot analysis of L-type Ca++ CP γ6 expression in WI 38 whole cell lysate.
Application
Western blot analysis of L-type Ca++ CP γ6 expression in Hep G2 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
