The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The TBX gene family encode for putative transcription factors that share a uniquely defining DNA-binding domain and are implicated in a variety of developmental processes, ranging from the formation of germ layers to the organizational patterning of the central nervous system. TBX genes encode a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates, one of which is TBX19, a 448 amino acid nuclear protein. Our understanding of functional mechanisms of TBX proteins has come mainly from the prototypical T/Brachyury, which is a transcriptional activator. Mutations in TBX genes are associated with the onset of several human diseases.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of TBX19 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of TBX19 of human origin by WB, IP and ELISA