Application
Western blot analysis of LMBR1 expression in Hep G2 whole cell lysate.Application
Western blot analysis of LMBR1 expression in EOC 20 whole cell lysate.| Product Name | LMBR1 Antibody (T-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | LMBR1 (limb region 1), also known as TPT, ACHP, PPD2 or DIF14, is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95% sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. SDYT4, an autosomal dominant trait, is a very rare congenital distal limb malformation characterized by complete bilateral syndactyly, which involves all five digits. LMBR1 exists as three alternatively spliced isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of LMBR1 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of LMBR1 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 64327 |
|---|
Application
Western blot analysis of LMBR1 expression in Hep G2 whole cell lysate.
Application
Western blot analysis of LMBR1 expression in EOC 20 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
