Application
Western blot analysis of CCDC19 expression in non-transfected: (A) and human CCDC19 transfected: (B) 293 whole cell lysates.Application
Western blot analysis of CCDC19 expression in HeLa (A) and Jurkat (B) whole cell lysates.Application
Western blot analysis of CCDC19 expression in Hep G2 whole cell lysate.| Product Name | CCDC19 Antibody (W-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of CCDC19 of human origin by WB, IP and ELISA |
| Modification Notes | CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson’s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of CCDC19 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of CCDC19 of human origin by WB, IP and ELISA |
| Entrez Gene | 25790 |
|---|
Application
Western blot analysis of CCDC19 expression in non-transfected: (A) and human CCDC19 transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of CCDC19 expression in HeLa (A) and Jurkat (B) whole cell lysates.
Application
Western blot analysis of CCDC19 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
