Application
Western blot analysis of ZIK1 expression in Jurkat whole cell lysate.| Product Name | ZIK1 Antibody (U-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which are thought to interact with KAP1, thereby recruiting histone modifying proteins. ZIK1 (zinc finger protein interacting with K protein 1 homolog), also known as ZNF762, is a 487 amino acid nuclear protein belonging to the krueppel C2H2-type zinc-finger protein family. Expressed at high levels in gastric glands, and at low levels in colon and small intestine, ZIK1 is silenced through promoter methylation in gastric glands with intestinal metaplasia. ZIK1 is considered a transcriptional repressor that interacts with hnRNP K. ZIK1 contains nine C2H2-type zinc fingers and a KRAB domain. Three isoforms of ZIK1 are produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ZIK1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of ZIK1 of human origin by WB, IP and ELISA |
| Entrez Gene | 284307 |
|---|
Application
Western blot analysis of ZIK1 expression in Jurkat whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
