Application
Western blot analysis of NUDT12 expression in Hep G2 whole cell lysate.| Product Name | NUDT12 Antibody (U-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | NUDT12 (nudix (nucleoside diphosphate linked moiety X)-type motif 12) is a 462 amino acid peroxisomal protein belonging to the nudix hydrolase family and the NudC subfamily. Nudix hydrolases contain a characteristic nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. NUDT12 functions as a manganese-dependent polyphosphate phosphohydrolase at an optimum pH of 8-9. Containing three ANK repeats and a nudix hydrolase domain, NUDT12 may act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors, which are required for oxidative metabolism in peroxisomes. The gene encoding NUDT12 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of NUDT12 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of NUDT12 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 83594 |
|---|
Application
Western blot analysis of NUDT12 expression in Hep G2 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
