The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCC13 is a 274 amino acid protein belonging to the MRP subfamily of the ABC transporter family. ABCC13 contains one ABC transmembrane type-1 domain, but does not contain Walker A, Walker B, and signature C motifs that are present in most ABC proteins, which indicates ABCC13 is not a functional transporter. ABCC13 has highest levels in colon and is present at lower levels in brain, liver, placenta, lung, ovary and pancreas. ABCC13 is expressed as five isoforms produced by alternative splicing.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ABCC13 of human origin by WB, IP, IF and ELISA non cross-reactive with other ABC family members also reactive with additional species, including equine, canine and bovine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ABCC13 of human origin
Tissue Specificity
epitope mapping within an internal region of ABCC13 of human origin
Western blot analysis of ABCC13 expression in HEK293 (A), Hep G2 (B), HeLa (C), SW480 (D), JAR (E) and A549 (F) whole cell lysates.
Application Notes
recommended for detection of ABCC13 of human origin by WB, IP, IF and ELISA non cross-reactive with other ABC family members also reactive with additional species, including equine, canine and bovine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.