| Modification Notes |
The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PTPN13LY (PTPN13-like, Y-linked), also known as PRY, PTPN13LY2 or PRY2, is a 147 amino acid protein that localizes to the testis and may function in a similar manner to PTP proteins. The gene encoding PTPN13LY maps to human chromosome Y and is expressed as two alternatively spliced isoforms. Chromosome Y contains approximately 58 million base pairs and houses over 80 genes, many of which are essential for proper sexual development. The Y chromosome is the human sex determining chromosome, necessary for male development and, while deletions or defects in chromosome Y-encoded genes are not lethal, they may greatly impair masculine development and function. |
