Application
Western blot analysis of IL-1Rrp2 expression in HL-60 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostata carcinoma tissue showing cytoplasmic staining.| Product Name | IL-1Rrp2 Antibody (C-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | IL-1Rrp2 (Interleukin-1 receptor-related protein 2) or IL1RL2, is a member of the interleukin-1/Toll-like receptor family and is highly expressed in brain, skin and mammary and mucosal epithelial cells. IL-1Rrp2 exhibits 42% homology with interleukin-1 type 1 receptor and 26% homology with interleukin-1 type 2 receptor. IL-1Rrp2 mediates NF-˚B activation, MAPK activation and inflammatory responses triggered by ligands IL-1F6, IL-1F8 and IL-1F9. Signalling via IL-1Rrp2 also requires IL-1RAcP (Interleukin-1 accessory protein). IL-1Rrp2 may play a role in immune defense in the GI tract and skin. IL-1Rrp2 may also be involved in the pathogenesis of rheumatoid arthritis (RA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of IL-1Rrp2 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of IL-1Rrp2 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 8808 |
|---|
Application
Western blot analysis of IL-1Rrp2 expression in HL-60 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostata carcinoma tissue showing cytoplasmic staining.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
