Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF444 (zinc finger protein 444), also known as EZF2 or Zinc finger and SCAN domain-containing protein 17 (ZSCAN17), is a 327 amino acid transcriptional regulator. ZNF444 localizes to the nucleus and contains four C2H2-type zinc fingers and one SCAN domain. The SCAN domain is a highly conserved motif that is found near the N-terminus of a subfamily of C2H2 zinc finger proteins. The SCAN domain helps to mediate self-association or selective association with other proteins bearing the SCAN domain. Two isoforms of ZNF444 exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of ZNF444 of mouse, rat, human and canine origin by WB, IP and ELISA