XTP3-transactivated gene A protein (XTP3TPA), also known as RS21-C6, is a 170 amino acid protein. Existing as a homotetramer, XTP3TPA contains an epilepsy-associated repeat (EAR) domain. The EAR domain spans about 44 amino acid residues and is predicted to participate in protein-protein interactions, most likely involved in ligand recognition. XTP3TPA is expressed in embryonic and highly proliferating cells, especially in liver, kidney, ovary and testis, with particularly high expression in cancer cells. One of the identified functions of XTP3TPA is to hydrolyze abnormal nucleotide triphosphates (NTPs) in cancer cells that, if unregulated, could be incorporated into nascent DNA or RNA.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of XTP3TPA of human origin by WB, IP, IF, IHC(P) and ELISA