Application
Western blot analysis of NOC4L expression in HeLa (A) and COLO 320DM (B) whole cell lysates.Application
Western blot analysis of NOC4L expression in Jurkat whole cell lysate.| Product Name | NOC4L Antibody (G-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from “classical” C/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC4L is a 516 amino acid multi-pass membrane protein that localizes to the nucleus and may be involved in cell cycle regulation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of NOC4L of human origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against NOC4L of human origin |
|---|---|
| Tissue Specificity | raised against NOC4L of human origin |
| Entrez Gene | 79050 |
|---|
Application
Western blot analysis of NOC4L expression in HeLa (A) and COLO 320DM (B) whole cell lysates.
Application
Western blot analysis of NOC4L expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of NOC4L of human origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
