Application
Western blot analysis of MANSC1 expression in non-transfected 293T: (A), mouse MANSC1 transfected 293T: (B) and Caki-1 (C) whole cell lysates.Application
Western blot analysis of MANSC1 expression in fetal kidney tissue extract.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human muscle tissue showing cytoplasmic staining.| Product Name | MANSC1 Antibody (Y-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | MANSC1 (MANSC domain-containing protein 1), also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of MANSC1 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against MANSC1 of human origin |
|---|---|
| Tissue Specificity | raised against MANSC1 of human origin |
| Entrez Gene | 54682 |
|---|
Application
Western blot analysis of MANSC1 expression in non-transfected 293T: (A), mouse MANSC1 transfected 293T: (B) and Caki-1 (C) whole cell lysates.
Application
Western blot analysis of MANSC1 expression in fetal kidney tissue extract.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human muscle tissue showing cytoplasmic staining.| Application Notes | recommended for detection of MANSC1 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
