Application
Western blot analysis of MIER3 expression in Jurkat nuclear extract.| Product Name | MIER3 Antibody (L-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The mesoderm induction early response (MIER) protein family is also known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, it is likely that the MIER proteins may play a significant role in FGF-regulated cellular activities, suggesting a potential influence in the progression of certain cancers. MIER proteins contain one SANT domain, a domain that has been characterized to be involved in transcriptional activation and repression, and one ELM2 domain, a domain which was first characterized in egl-27, a gene that is critically involved in embryonic patterning of C. elegans. Mesoderm induction early response protein 3 (MIER3) is a 550 amino acid protein that is localized to the nucleus and primarily functions as a transcriptional repressor. There are five known isoforms of MIER3 that are produced as a result of alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of MIER3 of human and canine origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against MIER3 of human origin |
|---|---|
| Tissue Specificity | raised against MIER3 of human origin |
| Entrez Gene | 166968 |
|---|
Application
Western blot analysis of MIER3 expression in Jurkat nuclear extract.| Application Notes | recommended for detection of MIER3 of human and canine origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
