Application
Western blot analysis of KV1.7 (U-22) expression in Jurkat whole cell lysate.| Product Name | KV1.7 Antibody (U-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels which vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å-subunits (KVå), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV∫ subunits that modify the gating properties of the coexpressed KVå subunits. KV1.7 is a 456 amino acid voltage-gated K+ channel protein highly expressed in heart, skeletal muscle and kidney. The tail of KV1.7 is thought to modulate channel activity while the N-terminus may be important for the activation rate of the channel. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of KV1.7 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against KV1.7 of human origin |
|---|---|
| Tissue Specificity | raised against KV1.7 of human origin |
| Entrez Gene | 3743 |
|---|
Application
Western blot analysis of KV1.7 (U-22) expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of KV1.7 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
