| Product Name | PIDD Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | PIDD (for p53 induced protein with a death domain) encodes a protein of 915 amino acids in mice (910 amino acids in humans) and contains seven tandem leucine rich repeats (LRR) in the amino terminus and a death domain in the carboxy terminus. PIDD mRNA is induced by g-irradiation in a p53-dependent manner and the basal level of PIDD mRNA is dependent on p53 status. Over-expression of PIDD inhibits cell growth in a p53-like manner by inducing apop-tosis. Antisense inhibition of PIDD expression has been shown to attenuate p53-mediated apoptosis, suggesting that PIDD expression is required for apoptosis. PIDD localizes to the cytosol. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PIDD of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 611-910 (deletion 704-720) mapping at the C-terminus of PIDD of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 611-910 (deletion 704-720) mapping at the C-terminus of PIDD of human origin |
| Entrez Gene | 55367 |
|---|
| Application Notes | recommended for detection of PIDD of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
