Application
Western blot analysis of POFUT2 expression in non-transfected: (A) and human POFUT2 transfected: (B) 293T whole cell lysates.| Product Name | POFUT2 Antibody (S-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. POFUT2 (Peptide-O-fucosyltransferase 2), also known as FUT13 or O-FucT-2, is a fucosyltransferase responsible for transferring fucose to serine or threonine residues in properly folded thrombospondin repeats (TSRs) through an O-glycosidic linkage. POFUT2 localizes to the endoplasmic reticulum and exists in three isoforms (designated A, B and C) which exhibit different patterns of expression. In addition, POFUT2 may have chaperone-like activity and function in quality control and protein folding. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of POFUT2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of POFUT2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of POFUT2 of human origin |
| Entrez Gene | 23275 |
|---|
Application
Western blot analysis of POFUT2 expression in non-transfected: (A) and human POFUT2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of POFUT2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
