| Product Name | STOP Antibody (H-230) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Microtubules in the cytoplasm of mammalian cells usually depolarize rapidly when exposed to cold temperature or to assembly-inhibiting drugs. Some cell types, however, contain sub-populations of microtubules called “cold-stable microtubules” that resist these depolymerizing conditions. This stabilization is due mainly to polymer association with a 952 amino acid neuronal protein designated STOP (stable tubule only polypeptide). The central region of STOP contains five tandem repeats of 46 amino acids. STOP also contains a SH3-binding motif near its N-terminus. It is present in the cell body and throughout the axon. The STOP protein action can be extreme, inducing resistance at temperatures as low as -80° C. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of STOP of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 61-290 mapping near the N-terminus of STOP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 61-290 mapping near the N-terminus of STOP of human origin |
| Entrez Gene | 17760 |
|---|
| Application Notes | recommended for detection of STOP of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
