| Product Name | GPA2 Antibody (FL-129) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Glycoprotein hormone a2 subunit (GPA2) belongs to the dimeric glycoprotein hormones a chain family. GPA2 is an N-linked glycosylated secreted protein with ten cysteine residues likely involved in cysteine-knot formation. It forms a heterodimer with glycoprotein hormone b5 subunit (GPB5), also called thyrostimulin hormone, and activates thyroid stimulating hormone receptor (also designated thyrotropin receptor or TSHR), which increases cAMP production and stimulates the thymus. GPA2 and GPB5 are both evolutionarily conserved and GPA2 may serve as a scaffold for GPB5 for downstream G protein-coupled signaling. GPA2 demonstrates ubiquitious expression and co-localizes with GPB5 in the eye, testis and pituitary (GPA2 detected in the anterior lobe). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GPA2 (Glycoprotein hormone alpha 2 precursor) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-129 representing full length GPA2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-129 representing full length GPA2 of human origin |
| Entrez Gene | 170589 |
|---|
| Application Notes | recommended for detection of GPA2 (Glycoprotein hormone alpha 2 precursor) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
