Kynurenine aminotransferases belong to the class-I pyridoxal-phosphate-dependent aminotransferase family and contain the members KAT I, KAT II, and KAT III. Kynurenine aminotransferases belong to the class-I pyridoxal-phosphate-dependent aminotransferase family and contain the members KAT I, KAT II, and KAT III. KAT II is a mitochondrial protein involved in lysine degradation. KAT II is expressed highly in liver, but can also be detected in heart, brain, kidney, pancreas, ovary, and testis. Like KAT I, KAT II functions in the catalysis of the reaction L-2-aminoadipate + 2-oxoglutarate --> 2-oxoglutaramate + L-glutamate. KAT II is thought to function as a homodimer.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of KAT II of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 126-425 mapping at the C-terminus of KAT II of mouse origin
Tissue Specificity
epitope corresponding to amino acids 126-425 mapping at the C-terminus of KAT II of mouse origin